For much of the 20th century, global conflicts and industrialization have come at the expense of human and nature's well-being. Today, we face the consequences of a global energy crisis, rising living expenses, extreme weather events, loss of biodiversity, and environmental pollution. To secure a more resilient future and protect our increasingly fragile environment, we must find new ways for humans to live in harmony with nature. This reality demands a total transformation of human living, one that views humans and nature as complementary, not opposing forces. Through the Science of Biotonomy, we learn how to infuse the intellect of nature in Architecture to develop Autonomous Buildings that will encourage humanity and the natural world to thrive as one.